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  • Upcoming Events

    The South African Pharmaceutical Exhibition (SAPHEX) is scheduled for March 5-6, 2025, at the Sandton Convention Centre in Johannesburg.

    SAPHEX stands as the premier event for professionals in South Africa's pharmaceutical manufacturing industry. The exhibition brings together key players, decision-makers, and suppliers, showcasing the latest innovations in APIs, excipients, packaging, and machinery. Attendees can expect to network, explore new advancements, and engage in discussions pivotal to the growth of the African pharmaceutical market.


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    Latest Medical Articles

    Unusual bleeding during and after pregnancy

    When should pregnant women be concerned? Awareness of the dangers associated with abnormal bleeding during pregnancy and after childbirth can be lifesaving for both women and their babies.

    Dr. Mzuvele Archwell Hlabisa, an obstetrician and gynaecologist at Netcare Kingsway Hospital, emphasizes that while many people are unaware that over a third of pregnant women may experience bleeding for various reasons, it is crucial to determine the exact cause.

    "Although some bleeding is normal in the postpartum period, excessive bleeding can be life-threatening. It is often difficult for women to discern if their bleeding is normal or not, but a good rule of thumb is to have any bleeding during pregnancy checked by a healthcare professional," says Dr. Hlabisa.

    He notes that around 35% of women experience bleeding in the first trimester. "As the pregnancy progresses, the likelihood of bleeding decreases, so it’s reassuring when women reach the mid-trimester, from 13 to 28 weeks of gestation."

    Bleeding could indicate a miscarriage or a threatened miscarriage, and severe pain with bleeding could be related to placental abruption, a serious condition where the placenta prematurely separates from the womb. These conditions require immediate medical assessment.

    Spotting In early pregnancy, some women may experience spotting, known as implantation bleeding, when the embryo implants in the uterine wall. ...Read full article

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    Global Medical News

    The Impact of NSAID Use on Dementia Risk: Duration Matters
    Nonsteroidal anti-inflammatory drugs (NSAIDs), such as ibuprofen, are commonly used to relieve pain, reduce inflammation, and lower fevers. While these medications are highly effective for symptom management, researchers are also exploring their potential long-term effects.

    A recent study published in the Journal of the American Geriatrics Society examined the relationship between NSAID use and dementia risk. Analyzing data from 11,745 participants, researchers found that using NSAIDs for more than two years was linked to a reduced risk of developing dementia. However, shorter-term use was associated with a slight increase in dementia risk.

    Interestingly, the total amount of NSAIDs taken did not influence dementia risk, emphasizing that the duration of use may play a crucial role in any potential protective effects.
    18 March 2025

    Swapping Butter for Plant-Based Oils Linked to Lower Risk of Premature Death
    A new study suggests that replacing butter with plant-based oils, particularly olive oil, soybean oil, and canola oil, may help reduce the risk of early death.

    Researchers found that substituting 10 grams of butter daily with an equivalent amount of plant-based oil was linked to a 17% decrease in overall mortality and a 17% reduction in cancer-related mortality. Experts emphasize the importance of incorporating healthy fats, especially those rich in omega-3 fatty acids, for overall well-being.

    The cohort study, recently published in JAMA Internal Medicine, analyzed data from over 200,000 participants across three major long-term studies: the Nurses’ Health Study (1990–2023), the Nurses’ Health Study II (1991–2023), and the Health Professionals Follow-up Study (1990–2023). The research focused on individuals who had no history of cancer, cardiovascular disease, diabetes, or neurodegenerative conditions.

    Participants’ butter consumption was assessed based on cooking and meal additions, while plant-based oil alternatives included olive oil, soybean oil, corn oil, canola oil, and safflower oil. Over a follow-up period of up to 33 years, participants completed food intake questionnaires at the start of the study and every four years.

    Findings indicated that replacing butter with plant-based oils was significantly associated with a lower risk of premature death, reinforcing the benefits of choosing healthier fat sources.








    17 March 2025

    Rise in Measles Cases Sparks Interest in Vitamin A Supplements: What Experts Say
    Measles cases have been on the rise in the United States, with over 200 reported across at least a dozen states. This outbreak has led to increased interest in vitamin A supplements as a potential treatment or preventive measure, following recent remarks by U.S. Health and Human Services Secretary Robert F. Kennedy Jr.

    As of March 7, the outbreak has affected more than 220 individuals, with one confirmed fatality and another under investigation. The most impacted areas include western Texas and New Mexico, while cases have also been recorded in California, New York, and Maryland. With spring break approaching, the Centers for Disease Control and Prevention (CDC) has advised travelers to remain cautious.

    Historically, measles has been a well-controlled disease in the U.S., with occasional outbreaks, such as the Minnesota outbreak in 2017 and the Indiana outbreak in 2005, both primarily driven by undervaccination.

    Secretary Kennedy has suggested that vitamin A—available in supplements like cod liver oil—along with the steroid budesonide and the antibiotic clarithromycin, has shown promise in treating measles. While the CDC acknowledges vitamin A as a potential treatment, it continues to emphasize vaccination as the most effective defense against measles.

    To provide clarity on the role of vitamin A and other preventive measures, Medical News Today consulted two medical experts: Dr. Monica Gandhi, an infectious disease specialist at the University of California, San Francisco, and Dr. Danelle Fisher, a board-certified pediatrician at Providence Saint John’s Health Center in Santa Monica, CA.







    14 March 2025

    Better Heart Health May Lower Risk of Neurodegenerative Diseases
    The American Heart Association’s Life’s Simple 7 serves as a guideline for managing seven modifiable risk factors for heart disease. Cardiovascular disease is also recognized as a risk factor for neurodegenerative conditions like Alzheimer’s disease and dementia.

    A recent study has identified a connection between higher Life’s Simple 7 scores in older adults and a potential reduction in biomarkers associated with neurodegenerative diseases. Researchers highlight the importance of improving cardiovascular health, particularly for Black and African American populations, who face a higher risk of both heart disease and dementia.

    Originally introduced in 2010, Life’s Simple 7 promotes healthier lifestyle choices—such as quitting smoking, maintaining a balanced diet, and managing body mass index (BMI)—to reduce the risk of cardiovascular conditions, including heart failure, hypertension, and coronary heart disease.

    The study, published in JAMA Network Open, emphasizes the potential impact of heart health education in preventing neurodegenerative diseases. According to lead author Dr. Anisa Dhana of Rush University Medical Center, Alzheimer’s disease and related dementias pose a significant challenge for older adults and their caregivers. She underscores that focusing on prevention could have substantial public health benefits.

    “Since cardiovascular disease and dementia share common risk factors, we aimed to explore the role of Life’s Simple 7 in the neurodegeneration process,” Dhana explained.
    14 March 2025

    The Potential Benefits of Intermittent Fasting in Reducing Blood Clot Risk
    Blood clot formation can lead to life-threatening conditions such as strokes and heart attacks, prompting experts to explore ways to reduce this risk. A recent study published in Life Metabolism suggests that intermittent fasting may help regulate the blood clotting process by increasing the production of indole-3-propionic acid (IPA) through gut microorganisms.

    Researchers conducted experiments involving 160 human participants, blood samples, and mice. Their findings indicate that intermittent fasting may inhibit platelet activation and clot formation. Further studies in mice also revealed that fasting could potentially reduce brain and heart damage caused by disruptions in blood flow. These findings highlight intermittent fasting as a possible strategy for lowering the risk of clot-related complications.
    12 March 2025

    Aspirin May Help Prevent Cancer Spread by Boosting Immune Response
    Around half of all people will receive a cancer diagnosis at some point in their lives, typically in their later years. Cancer is most treatable when it remains confined to its original location, but it can become more dangerous if cancer cells break away and spread to other parts of the body.

    Researchers investigating cancer metastasis have found that aspirin may help prevent the spread of cancer by enhancing the body's immune response. In a study conducted on mice, aspirin enabled immune cells to eliminate migrating cancer cells more effectively. Ongoing human research aims to determine whether aspirin or similar drugs could help delay or prevent cancer recurrence.

    According to Cancer Research UK, half of those diagnosed with cancer in Wales and England survive at least 10 years post-diagnosis, with even higher survival rates for common cancers. Data from 2013-2017 shows that over 75% of individuals diagnosed with breast or prostate cancer in England were still alive a decade later.

    Early detection plays a crucial role in successful treatment, as more than 90% of cancer-related deaths occur after the disease has metastasized. Now, scientists from the University of Cambridge have identified how aspirin, an inexpensive and widely available medication, might help prevent the spread of certain cancers.

    Published in Nature, the study found that aspirin affects platelets—the small blood cells responsible for clotting—by reducing their production of thromboxane A2 (TXA2), a clotting factor that suppresses immune T cells. With lower TXA2 levels, T cells are better able to attack and destroy cancer cells attempting to spread.







    11 March 2025
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