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Splenomegaly

Information from the Medical Directory health library.

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This information supports, and does not replace, advice from your healthcare professional.

Overview

Splenomegaly is the enlargement of the spleen, which can occur due to infections, liver diseases, blood disorders, or cancers, and may affect immune function.

Symptoms

Pain or fullness in the upper left abdomen Feeling full without eating much Anemia or fatigue Frequent infections Easy bleeding or bruising

Causes

Infections (mononucleosis, malaria, bacterial infections) Liver diseases such as cirrhosis Blood disorders (leukemia, lymphoma) Inflammatory diseases (rheumatoid arthritis, lupus)

Diagnosis

Physical examination of the abdomen Ultrasound, CT scan, or MRI Blood tests to detect underlying causes Bone marrow examination in some cases

Treatment

Treating the underlying cause (infection, liver disease, or blood disorder) Medications to manage symptoms Surgery (splenectomy) in severe or persistent cases Regular monitoring for complications

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