This information supports, and does not replace, advice from your healthcare professional.
Overview
Sickle cell anaemia is an inherited blood disorder in which red blood cells become abnormally shaped, reducing their ability to carry oxygen and causing blockages in blood vessels.
Symptoms
Fatigue and weakness Pain episodes (crises) in joints, chest, or abdomen Swelling in hands and feet Frequent infections Delayed growth and vision problems
Causes
Inherited mutation in the hemoglobin gene Both parents must carry the sickle cell trait
Diagnosis
Newborn screening Blood tests for hemoglobin electrophoresis
Treatment
Medications like hydroxyurea to reduce crises Blood transfusions Bone marrow or stem cell transplant in severe cases Pain management and infection prevention