This information supports, and does not replace, advice from your healthcare professional.
Overview
Primary biliary cholangitis is a chronic liver disease where the bile ducts are gradually destroyed, leading to bile accumulation and liver damage.
Symptoms
Fatigue and weakness Itching (pruritus) Dry eyes and mouth Yellowing of skin and eyes (jaundice)
Causes
Autoimmune attack on bile ducts Genetic susceptibility Environmental triggers
Diagnosis
Blood tests for liver function and autoimmune antibodies Imaging to assess bile ducts Liver biopsy in some cases
Treatment
Medications to improve bile flow (ursodeoxycholic acid) Management of symptoms Liver transplant in advanced disease