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Paget's disease of bone

Information from the Medical Directory health library.

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This information supports, and does not replace, advice from your healthcare professional.

Overview

Paget's disease of bone is a chronic disorder that can result in enlarged and misshapen bones due to abnormal bone destruction and regrowth.

Symptoms

Bone pain Deformities in bones Fractures occurring more easily Warmth over affected bones Hearing loss if skull bones are affected

Causes

Exact cause unknown Genetic factors Possible viral infection triggers

Diagnosis

X-rays showing characteristic bone changes Bone scans to detect affected areas Blood tests for elevated alkaline phosphatase levels

Treatment

Medications such as bisphosphonates Pain management with analgesics Orthopedic surgery if fractures or deformities occur Regular monitoring of bone health

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