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Non-Hodgkin lymphoma

Information from the Medical Directory health library.

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This information supports, and does not replace, advice from your healthcare professional.

Overview

Non-Hodgkin lymphoma (NHL) is a group of blood cancers that originate in the lymphatic system, affecting lymphocytes and causing lymph node swelling.

Symptoms

Swollen lymph nodes in neck, armpits, or groin Fever, night sweats, and unexplained weight loss Fatigue Abdominal pain or swelling Itchy skin

Causes

Genetic mutations in lymphocytes Weakened immune system Certain infections (e.g., EBV, HIV) Environmental factors and chemical exposures

Diagnosis

Physical examination Blood tests and imaging (CT, PET scans) Lymph node biopsy Bone marrow biopsy if needed

Treatment

Chemotherapy Radiation therapy Targeted therapy or immunotherapy Stem cell transplant in select cases

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