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Myopathy

Information from the Medical Directory health library.

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This information supports, and does not replace, advice from your healthcare professional.

Overview

Myopathy refers to diseases of the muscle in which the muscle fibers do not function properly, leading to muscle weakness and fatigue.

Symptoms

Progressive muscle weakness, especially in proximal muscles Muscle cramps or stiffness Difficulty climbing stairs or lifting objects Fatigue after minimal exertion

Causes

Genetic disorders (e.g., muscular dystrophies) Metabolic or endocrine disorders Inflammatory or autoimmune conditions Drug-induced or toxin-related muscle damage

Diagnosis

Physical examination and muscle strength testing Blood tests for muscle enzymes (CK) Electromyography (EMG) and muscle biopsy Genetic testing in suspected hereditary cases

Treatment

Depends on cause: immunosuppressive drugs, enzyme replacement, or medication adjustments Physical therapy to maintain muscle strength and mobility Assistive devices for daily activities Regular monitoring to prevent complications

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