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Hypoparathyroidism

Information from the Medical Directory health library.

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This information supports, and does not replace, advice from your healthcare professional.

Overview

Hypoparathyroidism is a rare condition where the parathyroid glands produce insufficient parathyroid hormone (PTH), leading to low calcium and high phosphate levels in the blood.

Symptoms

Muscle cramps or spasms (tetany) Burning or tingling in fingertips, toes, or lips Fatigue and weakness Dry skin and brittle nails Seizures in severe cases

Causes

Accidental damage or removal of parathyroid glands during neck surgery Autoimmune destruction of parathyroid glands Genetic disorders affecting parathyroid development Low magnesium levels affecting PTH secretion

Diagnosis

Blood tests: calcium, phosphate, magnesium, PTH levels ECG to detect heart rhythm disturbances Medical history and physical examination

Treatment

Calcium and vitamin D supplementation Magnesium supplements if needed Recombinant PTH therapy in selected cases Regular monitoring of blood calcium and phosphate

Complications

Seizures and muscle spasms Cardiac arrhythmias Dental problems and cataracts

Prevention

Careful surgical techniques to avoid parathyroid damage Early detection and treatment of autoimmune or genetic causes

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