Overview
Hughes syndrome , also called antiphospholipid syndrome, is an autoimmune disorder that increases the risk of blood clots, miscarriage, and other vascular problems.
Symptoms
Blood clots in veins or arteries Recurrent miscarriages or complications in pregnancy Stroke or transient ischemic attacks (TIAs) Skin rashes such as livedo reticularis
Causes
Autoimmune production of antiphospholipid antibodies Genetic predisposition Associated autoimmune conditions like lupus
Diagnosis
Blood tests for anticardiolipin and lupus anticoagulant antibodies Assessment of clotting history and pregnancy complications Imaging for blood clots if necessary
Treatment
Blood-thinning medications such as warfarin or heparin Low-dose aspirin for some patients Careful monitoring during pregnancy
Complications
Deep vein thrombosis (DVT) and pulmonary embolism Stroke or heart attack Pregnancy loss or complications
Prevention
Regular monitoring and adherence to medication Healthy lifestyle to reduce clot risk Management of associated autoimmune conditions