Skip to content
Customer support: +27 11 333 6000

YOUR HEALTH, BETTER UNDERSTOOD

Gangrene

Information from the Medical Directory health library.

Browse A–Z ↗
This information supports, and does not replace, advice from your healthcare professional.

Overview

Gangrene is the death of body tissue due to lack of blood flow or a severe bacterial infection. It commonly affects extremities such as toes, fingers, or limbs.

Symptoms

Discoloration of skin (black, blue, or green) Swelling or numbness Foul-smelling discharge Severe pain in the affected area

Causes

Poor blood circulation due to diabetes or atherosclerosis Severe injury or trauma Infections caused by bacteria such as Clostridium

Diagnosis

Physical examination Blood tests for infection Imaging tests to determine extent of tissue death

Treatment

Immediate antibiotics for infection Surgery to remove dead tissue (debridement) Amputation in severe cases Hyperbaric oxygen therapy in some cases

Complications

Sepsis (life-threatening infection) Loss of limb Death if untreated

Prevention

Manage diabetes and vascular diseases Prompt treatment of infections and wounds Maintain good hygiene and protect extremities

← Back to health conditions A–Z