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Erythema nodosum

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This information supports, and does not replace, advice from your healthcare professional.

Overview

Erythema nodosum is an inflammatory condition characterized by tender red nodules, usually on the shins, often triggered by infections, medications, or autoimmune conditions.

Symptoms

Painful red or purple nodules, typically on the front of the legs Fever and fatigue in some cases Joint pain or swelling

Causes

Infections: streptococcal infections, tuberculosis Medications: antibiotics, oral contraceptives Autoimmune conditions: sarcoidosis, inflammatory bowel disease

Diagnosis

Clinical examination of the nodules Blood tests for inflammation Throat swabs or imaging if underlying cause suspected

Treatment

Treat underlying cause Nonsteroidal anti-inflammatory drugs (NSAIDs) for pain Rest and elevation of affected limbs

Complications

Rare chronic nodules Persistent pain or discomfort

Prevention

Prompt treatment of infections Avoid triggers such as known medications if possible

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