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Erythema multiforme

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This information supports, and does not replace, advice from your healthcare professional.

Overview

Erythema multiforme is a skin reaction that causes red, target-shaped lesions, often triggered by infections or medications.

Symptoms

Red or purple target-shaped skin lesions Itching or burning sensation Blisters or ulcers in severe cases Possible mild fever or malaise

Causes

Viral infections (e.g., herpes simplex) Bacterial infections Medications such as antibiotics or anti-seizure drugs

Diagnosis

Clinical examination of skin lesions Skin biopsy if needed Review of recent medications and infections

Treatment

Treat underlying infection or stop causative medication Topical corticosteroids or oral medications for inflammation Pain relief and supportive skin care

Complications

Severe skin blistering or infection Rare progression to Stevens-Johnson syndrome

Prevention

Avoid known triggers such as certain medications Prompt treatment of infections

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