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Diphtheria

Information from the Medical Directory health library.

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This information supports, and does not replace, advice from your healthcare professional.

Overview

Diphtheria is a serious bacterial infection affecting the throat and nose, caused by *Corynebacterium diphtheriae*. It can lead to breathing difficulties, heart failure, and nerve damage if untreated.

Symptoms

Sore throat and difficulty swallowing Thick, gray coating in the throat or nose Fever and chills Swollen neck glands (“bull neck” appearance)

Causes

Infection with *Corynebacterium diphtheriae* Transmission through respiratory droplets or contact with infected objects

Diagnosis

Throat swab for bacterial culture Physical examination of symptoms Laboratory testing for toxin production

Treatment

Antitoxin to neutralize bacterial toxin Antibiotics such as penicillin or erythromycin Supportive care for breathing and heart issues

Complications

Myocarditis (heart inflammation) Nerve damage and paralysis Respiratory obstruction Death if untreated

Prevention

Vaccination with DTP or Tdap vaccine Good hygiene and avoiding contact with infected individuals

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