18 March 2025

The Impact of NSAID Use on Dementia Risk: Duration Matters

Nonsteroidal anti-inflammatory drugs (NSAIDs), such as ibuprofen, are commonly used to relieve pain, reduce inflammation, and lower fevers. While these medications are highly effective for symptom management, researchers are also exploring their potential long-term effects.

A recent study published in the Journal of the American Geriatrics Society examined the relationship between NSAID use and dementia risk. Analyzing data from 11,745 participants, researchers found that using NSAIDs for more than two years was linked to a reduced risk of developing dementia. However, shorter-term use was associated with a slight increase in dementia risk.

Interestingly, the total amount of NSAIDs taken did not influence dementia risk, emphasizing that the duration of use may play a crucial role in any potential protective effects.